FINE Trial: Nurse-led Treatment for Chronic Fatigue Syndrome
Author Information
Author(s): Wearden AJ, Riste L, Dowrick C, Chew-Graham C, Bentall RP, Morriss RK, Peters S, Dunn G, Richardson G, Lovell K, Powell P
Primary Institution: University of Manchester
Hypothesis
Is pragmatic rehabilitation, delivered at home by nurses to CFS/ME patients recruited from primary care, a clinically effective intervention in terms of reduced disability and fatigue when compared with treatment as usual delivered through the primary care team?
Conclusion
The study aims to determine if nurse-led pragmatic rehabilitation is effective for chronic fatigue syndrome in primary care.
Supporting Evidence
- Chronic fatigue syndrome has a poor prognosis and serious consequences.
- Previous studies suggest cognitive behaviour therapy and graded exercise therapy are effective but not widely available.
- This trial will be the first adequately controlled trial of treatment for chronic fatigue syndrome in primary care.
Takeaway
This study is testing if nurses can help people with chronic fatigue feel better by using a special treatment plan.
Methodology
A single-blind, pragmatic randomized controlled trial comparing nurse-led pragmatic rehabilitation, supportive listening, and treatment as usual.
Potential Biases
Potential biases from therapist effects and patient willingness to be randomized.
Limitations
The study may face challenges in patient recruitment and adherence to treatment.
Participant Demographics
Patients aged 18 and over fulfilling the Oxford criteria for CFS.
Digital Object Identifier (DOI)
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