Yeast 2000; 17: 7980.
2000
Advancements in Proteomics and Genomics
publication
Author Information
Author(s): Paul Haynes, John Yates, Albertha Walhout, Simon Boulton, Marc Vidal, Fromont-Racine, Brosch, Steve Russell, Rachel Drysdale, Leyla Bayraktaroglu
Conclusion
The review discusses the current state and advancements in proteomics and comparative genomics, highlighting new techniques and findings.
Supporting Evidence
- Mass spectrometry is a common final step in proteomics.
- Two-hybrid screening is used to identify protein interaction partners.
- Genome-wide two-hybrid screens have been advanced in yeast and C. elegans.
- Comparative genomics studies are beneficial for understanding pathogens.
- The Mouse Genome Informatics site provides extensive data on mouse genomics.
- The completion of the Drosophila genome has increased interest in sequencing databases.
Takeaway
Scientists are learning more about proteins and their interactions, which helps us understand how they work together in living things.
Methodology
The review covers various analytical methods in proteomics, including mass spectrometry and two-hybrid screening.
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