Prognostic factors in a T3 bladder cancer trial
1989

Prognostic Factors in T3 Bladder Cancer

Sample size: 394 publication Evidence: moderate

Author Information

Author(s): A. Babiker, R.J. Shearer, C.E.D. Chilvers

Primary Institution: Co-operative Urological Cancer Group

Hypothesis

What are the prognostic factors affecting survival in patients with T3 bladder cancer?

Conclusion

Primary tumour size is the most significant prognostic factor for survival in T3 bladder cancer patients.

Supporting Evidence

  • Primary tumour size was found to be the single most powerful prognostic factor.
  • Nodal status was the second most predictive variable.
  • Three prognostic groups were proposed based on tumour size and nodal status.

Takeaway

This study looked at what factors can help predict how long patients with a certain type of bladder cancer might live. It found that the size of the tumor is really important.

Methodology

The study analyzed data from 394 patients with T3 bladder cancer, examining various prognostic factors and their impact on survival.

Potential Biases

There may be biases related to the selection of patients and the accuracy of recorded data.

Limitations

The study may not account for all potential prognostic factors and relies on historical data.

Participant Demographics

The median age of participants was 69 years, with a mix of men and women.

Statistical Information

P-Value

P=0.002

Confidence Interval

95% CI 57.2 and 96.4

Statistical Significance

p<0.05

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