Oh my aching gut: irritable bowel syndrome, Blastocystis, and asymptomatic infection
2008

Understanding Blastocystis and Its Role in Irritable Bowel Syndrome

publication Evidence: moderate

Author Information

Author(s): Kenneth F Boorom, Huw Smith, Laila Nimri, Eric Viscogliosi, Gregory Spanakos, Unaiza Parkar, Lan-Hua Li, Xiao-Nong Zhou, Z Ülgen Ok, Saovanee Leelayoova, Morris S Jones

Primary Institution: Blastocystis Research Foundation

Hypothesis

Is Blastocystis a pathogenic organism contributing to irritable bowel syndrome (IBS) symptoms?

Conclusion

Blastocystis may play a significant role in chronic gastrointestinal illnesses, including IBS, but its pathogenicity remains controversial.

Supporting Evidence

  • Blastocystis is commonly found in humans and has been linked to various gastrointestinal symptoms.
  • Studies show that Blastocystis infection rates are high in patients with IBS.
  • Conflicting reports exist regarding the pathogenicity of Blastocystis, with some studies suggesting it is non-pathogenic.

Takeaway

Blastocystis is a tiny bug that can make your tummy hurt, but sometimes it doesn't cause any problems at all.

Methodology

The review discusses various studies and diagnostic methods related to Blastocystis infections and their association with IBS.

Potential Biases

Conflicting results may arise from differences in study populations and diagnostic techniques.

Limitations

The review highlights the variability in diagnostic methods and the lack of consensus on the pathogenicity of Blastocystis.

Digital Object Identifier (DOI)

10.1186/1756-3305-1-40

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