Fournier’s Gangrene Severity Index and Charlson Comorbidity Index Predict Outcomes in Patients
Author Information
Author(s): Muacevic Alexander, Adler John R, Hauser Nicholas, Huang Chenlin, Vaidya Girija, Chrusciel Timothy, Narayana Kumarasan Krithika, Culhane John, Siddiqui Sameer
Primary Institution: Saint Louis University School of Medicine
Hypothesis
Can the Fournier's Gangrene Severity Index and Charlson Comorbidity Index predict mortality, ICU admission, and length of hospital stay in patients with Fournier's gangrene?
Conclusion
The study found that FGSI and CCI scores can predict patient outcomes such as ICU admission and length of hospital stay, but diabetes status does not predict more severe disease.
Supporting Evidence
- Diabetes status did not predict worse outcomes in patients with Fournier's gangrene.
- FGSI scores were significantly associated with mortality and ICU admission.
- CCI scores were also associated with mortality but not with ICU admission.
- Patients with higher FGSI scores had longer hospital stays.
- Insulin use did not correlate with worse outcomes in diabetic patients.
Takeaway
Doctors can use special scores to figure out how sick someone with Fournier's gangrene might get and how long they might stay in the hospital.
Methodology
A multicenter retrospective case series analyzing inpatient admissions with Fournier's gangrene from 2013 to 2023 using logistic regression and generalized linear regression models.
Potential Biases
The study's retrospective nature may introduce bias in data collection and analysis.
Limitations
All patients were male, and there was a lack of hemoglobin A1c data to assess diabetes control.
Participant Demographics
All male patients with a mean age of 54.7 years.
Statistical Information
P-Value
p<0.0001 for FGSI and p=0.003 for CCI regarding mortality.
Confidence Interval
1.14 (1.1, 1.2) for FGSI and 1.2 (1.1, 1.4) for CCI regarding mortality.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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