Fournier’s Gangrene Severity Index and Charlson Comorbidity Index Predict Mortality, Intensive Care Unit Admission, and Length of Hospital Stay in Patients With Fournier’s Gangrene: An Analysis of 264 Consecutive Patients
2024

Fournier’s Gangrene Severity Index and Charlson Comorbidity Index Predict Outcomes in Patients

Sample size: 264 publication Evidence: high

Author Information

Author(s): Muacevic Alexander, Adler John R, Hauser Nicholas, Huang Chenlin, Vaidya Girija, Chrusciel Timothy, Narayana Kumarasan Krithika, Culhane John, Siddiqui Sameer

Primary Institution: Saint Louis University School of Medicine

Hypothesis

Can the Fournier's Gangrene Severity Index and Charlson Comorbidity Index predict mortality, ICU admission, and length of hospital stay in patients with Fournier's gangrene?

Conclusion

The study found that FGSI and CCI scores can predict patient outcomes such as ICU admission and length of hospital stay, but diabetes status does not predict more severe disease.

Supporting Evidence

  • Diabetes status did not predict worse outcomes in patients with Fournier's gangrene.
  • FGSI scores were significantly associated with mortality and ICU admission.
  • CCI scores were also associated with mortality but not with ICU admission.
  • Patients with higher FGSI scores had longer hospital stays.
  • Insulin use did not correlate with worse outcomes in diabetic patients.

Takeaway

Doctors can use special scores to figure out how sick someone with Fournier's gangrene might get and how long they might stay in the hospital.

Methodology

A multicenter retrospective case series analyzing inpatient admissions with Fournier's gangrene from 2013 to 2023 using logistic regression and generalized linear regression models.

Potential Biases

The study's retrospective nature may introduce bias in data collection and analysis.

Limitations

All patients were male, and there was a lack of hemoglobin A1c data to assess diabetes control.

Participant Demographics

All male patients with a mean age of 54.7 years.

Statistical Information

P-Value

p<0.0001 for FGSI and p=0.003 for CCI regarding mortality.

Confidence Interval

1.14 (1.1, 1.2) for FGSI and 1.2 (1.1, 1.4) for CCI regarding mortality.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.75281

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