The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review
2024

Managing and Preventing Delirium in Elderly ICU Patients

Sample size: 14711 publication Evidence: moderate

Author Information

Author(s): Zaher-Sánchez Sarai, Satústegui-Dordá Pedro José, Ramón-Arbués Enrique, Santos-Sánchez Jose Angel, Aguilón-Leiva Juan José, Pérez-Calahorra Sofía, Juárez-Vela Raúl, Sufrate-Sorzano Teresa, Angulo-Nalda Beatriz, Garrote-Cámara María Elena, Santolalla-Arnedo Iván, Echániz-Serrano Emmanuel

Primary Institution: Miguel Servet Hospital, Aragonese Health Service

Hypothesis

What interventions are effective for managing and preventing delirium in elderly patients in intensive care units?

Conclusion

Dexmedetomidine is a viable option for sedation in ICU patients, and bright light therapy can reduce the incidence of delirium.

Supporting Evidence

  • Delirium affects 10-30% of hospitalized older adults.
  • ICU delirium can lead to longer hospital stays and increased mortality.
  • Bright light therapy improved sleep/wake cycles and reduced delirium incidence.
  • Dexmedetomidine showed a greater sedative effect compared to olanzapine.

Takeaway

Delirium is a common problem for older patients in the ICU, but certain treatments like bright light therapy and dexmedetomidine can help reduce it.

Methodology

A systematic review of studies from January 2018 to August 2024, including randomized clinical trials and cohort studies.

Potential Biases

Potential biases due to differences in patient characteristics and sedation protocols.

Limitations

Variability in definitions and assessment tools for delirium across studies limits the robustness of conclusions.

Participant Demographics

Participants were elderly patients aged 65 and older admitted to ICUs.

Digital Object Identifier (DOI)

10.3390/nursrep14040219

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