The Gene Ontology Annotation (GOA) project -- application of GO in SWISS-PROT, TrEMBL and InterPro
2003
The Gene Ontology Annotation (GOA) Project
publication
Evidence: moderate
Author Information
Author(s): Evelyn Camon, Daniel Barrell, Catherine Brooksbank, Michele Magrane, Rolf Apweiler
Primary Institution: European Bioinformatics Institute (EBI)
Conclusion
The GOA project significantly contributes to the understanding of proteomes by providing over 2.5 million GO associations across various protein entries.
Supporting Evidence
- The GOA project has assigned GO terms to all complete and incomplete proteomes in SWISS-PROT and TrEMBL.
- GOA files are updated monthly to reflect the latest data.
- The project aims to enhance the understanding of proteomes by providing functional information on proteins.
Takeaway
The GOA project helps scientists understand what proteins do by organizing information about them in a way that's easy to search and use.
Methodology
The project uses a combination of electronic mappings and manual curation to assign GO terms to proteins.
Limitations
The project currently covers only 64% of the SWISS-PROT and TrEMBL data, with plans to increase this coverage.
Digital Object Identifier (DOI)
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