Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industry
2008

Assessing PCE Exposure in Dry Cleaning Workers

Sample size: 18 publication Evidence: moderate

Author Information

Author(s): Laurel McKernan, Avima Ruder, Martin R. Petersen, Misty J. Hein, Christy L. Forrester, Wayne T. Sanderson, David L. Ashley, Mary A. Butler

Primary Institution: Centers for Disease Control and Prevention (CDC)

Hypothesis

The study aimed to assess the feasibility of conducting biological exposure assessments for tetrachloroethylene (PCE) among dry cleaning employees.

Conclusion

The study found that PCE levels in exhaled breath increased throughout the work week, and biological monitoring indicated that PCE in blood is the preferred index for exposure assessment.

Supporting Evidence

  • PCE in blood is the preferred biological index for monitoring exposures.
  • Post-shift PCE in exhaled breath increased throughout the work week.
  • Statistically significant correlations were observed among exposure indices.
  • Decreases in PCE in exhaled breath and TCA in urine were noted after two days without exposure.

Takeaway

This study looked at how much PCE, a chemical used in dry cleaning, workers breathe in and how it affects their health. It found that women working in dry cleaning can have higher levels of this chemical in their bodies.

Methodology

The study involved monitoring 18 female workers from four dry cleaning facilities, collecting air, blood, breath, and urine samples over several days to assess PCE exposure.

Potential Biases

Self-selection of facilities and participants may introduce bias, as those with higher PCE levels may have declined to participate.

Limitations

The study faced challenges with fluctuating work schedules and self-selection of facilities and participants, which may not represent the broader industry.

Participant Demographics

Participants were 18 female dry cleaning workers, with a mean age of 41 years and a mean BMI of 28; 72% were white and 56% were current smokers.

Statistical Information

P-Value

0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-069X-7-12

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