Images of colonic real-time tissue sonoelastography correlate with those of colonoscopy and may predict response to therapy in patients with ulcerative colitis
2011

Sonoelastography and Colonoscopy in Ulcerative Colitis

Sample size: 37 publication Evidence: moderate

Author Information

Author(s): Ishikawa Daisuke, Ando Takafumi, Watanabe Osamu, Ishiguro Kazuhiro, Maeda Osamu, Miyake Nobuyuki, Nakamura Masanao, Miyahara Ryoji, Ohmiya Naoki, Hirooka Yoshiki, El-Omar Emad M, Goto Hidemi

Primary Institution: Nagoya University Graduate School of Medicine

Hypothesis

Can real-time tissue sonoelastography predict therapy response in ulcerative colitis patients?

Conclusion

Sonoelastography findings correlate with colonoscopic findings and disease activity in ulcerative colitis patients.

Supporting Evidence

  • EG findings showed a significant correlation with colonoscopic findings.
  • 70% of patients with normal EG findings were in remission.
  • All patients with random-type EG findings were in the active phase.

Takeaway

Doctors used a special ultrasound technique to see how soft or hard the tissue in the colon is, which helps them understand how sick someone is with ulcerative colitis.

Methodology

Patients underwent both sonoelastography and colonoscopy, with findings classified into types based on tissue characteristics.

Potential Biases

Participation bias may exist as all patients were from one institution.

Limitations

The study had a small sample size and was conducted at a single institution, which may limit generalizability.

Participant Demographics

37 patients (16 males, 21 females, average age 44.3 years) with ulcerative colitis.

Statistical Information

P-Value

0.046

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1471-230X-11-29

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