Modern Management of Clinical Chorioamnionitis
Author Information
Author(s): Thomas Westover, Robert A. Knuppel
Primary Institution: Robert Wood Johnson Medical School Peter's Medical Center, University of Medicine and Dentistry of New Jersey
Conclusion
Advances in understanding and managing chorioamnionitis have led to improved maternal and neonatal outcomes.
Supporting Evidence
- Clinical chorioamnionitis is diagnosed with symptoms like fever and uterine tenderness.
- Histologic chorioamnionitis is found in 18% of term deliveries and 32% of preterm deliveries.
- Severe histologic chorioamnionitis is rarely found in afebrile patients.
- Advances in management have reduced maternal mortality rates associated with chorioamnionitis.
Takeaway
Chorioamnionitis is an infection during pregnancy that can make both mothers and babies very sick, but doctors have learned better ways to treat it over the years.
Methodology
This review summarizes the history, incidence, pathophysiology, risk factors, diagnosis, and management of clinical chorioamnionitis.
Limitations
The review does not provide definitive conclusions regarding the effect of placental histology on fetal or neonatal prognosis.
Participant Demographics
The study involved a review of cases from various populations, including over 1,800 singleton placentas.
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