The link between periodontal disease and cardiovascular disease: How far we have come in last two decades?
2010

The Link Between Gum Disease and Heart Disease

Sample size: 9760 publication 10 minutes Evidence: moderate

Author Information

Author(s): Dhadse Prasad, Gattani Deepti, Mishra Rohit

Primary Institution: Hitkarini Dental College and Hospital

Hypothesis

Is there a causal relationship between periodontal disease and cardiovascular disease?

Conclusion

There is a moderate association between periodontal disease and cardiovascular disease, but causality remains unclear.

Supporting Evidence

  • Periodontal disease is common and may contribute to cardiovascular risk.
  • Studies show varying degrees of association between periodontal disease and heart disease.
  • Some studies indicate that periodontal infections can lead to systemic inflammation affecting heart health.

Takeaway

This study looks at how gum disease might be linked to heart problems. It suggests that taking care of your teeth could help your heart.

Methodology

The review analyzes various epidemiological studies, including case-control, cohort, and cross-sectional studies, to assess the relationship between periodontal disease and cardiovascular disease.

Potential Biases

Potential biases may arise from residual confounding and the difficulty in controlling for all lifestyle factors.

Limitations

The evidence is mixed, and many studies have small sample sizes or lack rigorous controls for confounding factors.

Participant Demographics

The studies included diverse populations, with a focus on adults, particularly in the United States and India.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI [1.08–1.32]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0972-124X.75908

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