Efficacy of brain-computer interface training with motor imagery-contingent feedback in improving upper limb function and neuroplasticity among persons with chronic stroke: a double-blinded, parallel-group, randomized controlled trial

2025

Brain-Computer Interface Training Improves Upper Limb Function in Chronic Stroke

Sample size: 25 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kim Myeong Sun, Park Hyunju, Kwon Ilho, An Kwang-Ok, Kim Hayeon, Park Gyulee, Hyung Wooseok, Im Chang-Hwan, Shin Joon-Ho

Primary Institution: Translational Research Center for Rehabilitation Robots, National Rehabilitation Center, Ministry of Health and Welfare, Seoul, Korea

Hypothesis

BCI training with MI-contingent feedback would result in greater improvements in upper limb function and neural plasticity compared to BCI training with MI-independent feedback.

Conclusion

BCI training with MI-contingent feedback is more effective than MI-independent feedback in improving upper limb function and neural plasticity in individuals with chronic stroke.

Supporting Evidence

The MI-contingent feedback BCI group showed significantly greater improvements in MRC-WE scores.
The MI-contingent feedback BCI group demonstrated increased AROM-WE at 4 weeks post-intervention.
Enhanced functional connectivity in the affected hemisphere was observed in the MI-contingent feedback BCI group.

Takeaway

Using a special brain-computer interface that gives feedback based on your thoughts can help people with stroke move their arms better.

Methodology

This was a double-blinded, parallel-group, randomized controlled trial involving chronic stroke patients who underwent BCI training with either MI-contingent or MI-independent feedback.