AI predictive models and advancements in microdissection testicular sperm extraction for non-obstructive azoospermia: a systematic scoping review
2024

AI Models and Testicular Sperm Extraction for Male Infertility

Sample size: 11636 publication Evidence: moderate

Author Information

Author(s): Hossein Jamalirad, Mahdie Jajroudi, Bahareh Khajehpour, Mohammad Ali Sadighi Gilani, Saeid Eslami, Marjan Sabbaghian, Hassan Vakili Arki

Primary Institution: Mashhad University of Medical Sciences, Mashhad, Iran

Hypothesis

How accurately can artificial intelligence (AI) models predict sperm retrieval in non-obstructive azoospermia (NOA) patients undergoing micro-testicular sperm extraction (m-TESE) surgery?

Conclusion

AI predictive models hold significant promise in predicting successful sperm retrieval in NOA patients undergoing m-TESE, although limitations regarding variability of study designs, small sample sizes, and a lack of validation studies restrict the overall generalizability of studies in this area.

Supporting Evidence

  • AI models can analyze various factors to predict sperm retrieval success.
  • Machine learning techniques have shown promise in improving predictions for sperm retrieval.
  • Limitations include small sample sizes and variability in study designs.

Takeaway

Doctors can use AI to help predict if a man with a specific type of infertility will be able to get sperm from his testicles, which can help couples have babies.

Methodology

A systematic scoping review was conducted following PRISMA-ScR guidelines, covering PubMed and Scopus databases from 2013 to May 2024.

Potential Biases

All included studies demonstrated a low risk of bias and minimal concerns regarding applicability.

Limitations

The review includes heterogeneity of included studies, potential publication bias, and reliance on only two databases, which may limit the findings.

Participant Demographics

The review covered information from 11,636 patients with NOA who had undergone m-TESE.

Digital Object Identifier (DOI)

10.1093/hropen/hoae070

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