Integration of Solexa sequences on an ultradense genetic map in Brassica rapa L.
2011

Creating a Detailed Genetic Map for Brassica rapa

Sample size: 92 publication 10 minutes Evidence: high

Author Information

Author(s): Li Wei, Zhang Jiefu, Mou Yanglong, Geng Jianfeng, McVetty Peter BE, Hu Shengwu, Li Genyi

Primary Institution: College of Agronomy, Northwest A&F University

Hypothesis

Can next generation sequencing be effectively integrated with SRAP to construct a high-density genetic map in Brassica rapa?

Conclusion

An ultradense genetic map with 10,960 independent genetic loci in Brassica rapa was constructed using SRAP and next generation sequencing.

Supporting Evidence

  • The ultradense genetic map was constructed using 9,177 SRAP markers and 1,737 integrated unique Solexa paired-end sequences.
  • The genetic map covered a genetic distance of 1,495.6 cM.
  • 141 unique Solexa paired-end sequences were matched with their corresponding SRAP markers.

Takeaway

Scientists made a super detailed map of a plant's genes using special technology that helps them see many tiny parts of the plant's DNA.

Methodology

The study used SRAP and Illumina's Solexa sequencing to analyze a recombinant inbred line mapping population.

Limitations

The study may have limitations related to the accuracy of scoring polymorphic loci due to variations in PCR conditions.

Participant Demographics

The study involved a mapping population developed from a yellow seeded Brassica rapa variety and a Chinese cabbage doubled haploid line.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2164-12-249

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