Mortality from Community-Acquired MRSA Infections
Author Information
Author(s): Delaney JA 'Chris', Schneider-Lindner Verena, Brassard Paul, Suissa Samy
Primary Institution: McGill University Health Center
Hypothesis
What is the mortality associated with community-acquired MRSA infections?
Conclusion
MRSA infections diagnosed in the community are associated with significant mortality in the year after diagnosis.
Supporting Evidence
- 21.8% of MRSA patients died within one year compared to 5.0% of non-MRSA patients.
- The adjusted hazard ratio for death in MRSA patients was 4.1.
- Patients with MRSA were more likely to have co-morbid conditions.
Takeaway
Getting an MRSA infection in the community can make you very sick and even lead to death, especially within a year of being diagnosed.
Methodology
A cohort study using the UK General Practice Research Database to compare mortality in patients with and without MRSA.
Potential Biases
Residual confounding due to unmeasured health states that predispose to MRSA infections.
Limitations
Could not distinguish site or severity of individual MRSA infections and potential confounding factors were not fully controlled.
Participant Demographics
Patients were older than 18 years, with a mean age of 70 years; included both males and females.
Statistical Information
P-Value
4.08
Confidence Interval
3.5–4.7
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website