Free radical theory of autoimmunity
2006
Free Radical Theory of Autoimmunity
publication
Author Information
Author(s): Kannan Subburaj
Primary Institution: University of Texas Medical Branch
Hypothesis
A hypothetical scheme to explain the damage induced by chemotherapy and associated chronic oxidative stress is proposed.
Conclusion
The argument suggests a possible mechanism for the development of autoimmunity related to chemotherapy-induced damage.
Supporting Evidence
- Chemotherapy can induce oxidative stress that affects immune function.
- Chronic oxidative stress may lead to the development of autoimmunity.
- Autoimmune responses can be triggered by the damage caused by chemotherapeutic agents.
Takeaway
Chemotherapy can cause damage that might lead to autoimmune diseases by affecting how the immune system works.
Methodology
The article reviews literature and experimental data to propose a hypothesis.
Digital Object Identifier (DOI)
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