Alveolar Hemorrhage After Stem Cell Transplant Due to Strongyloides Infection
Author Information
Author(s): Gupta Sachin, Jain Amit, Fanning Tina V, Couriel Daniel R, Jimenez Carlos A, Eapen Georgie A
Primary Institution: The University of Texas M.D. Anderson Cancer Center
Hypothesis
Strongyloides stercoralis hyperinfection may cause diffuse alveolar hemorrhage in patients post hematopoietic stem cell transplantation.
Conclusion
Strongyloides stercoralis hyperinfection is a rare but serious cause of alveolar hemorrhage after hematopoietic stem cell transplantation, leading to high mortality.
Supporting Evidence
- Strongyloides hyperinfection has a mortality exceeding 80%.
- Screening for Strongyloides prior to HSCT may improve outcomes.
- The patient developed respiratory failure and died 14 days after diagnosis.
Takeaway
Sometimes, after a special cancer treatment called stem cell transplant, a tiny bug can make people very sick and cause serious lung problems.
Methodology
Case report detailing the clinical presentation, treatment, and outcomes of a patient with Strongyloides hyperinfection after HSCT.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
52-year old Puerto Rican male.
Digital Object Identifier (DOI)
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