Floating Tablets of Liquorice Extract for Stomach Treatment
Author Information
Author(s): Ram H. N. Aswatha, Lachake Prachiti, Kaushik Ujjwal, Shreedhara C. S.
Primary Institution: Manipal College of Pharmaceutical Sciences, Manipal University
Hypothesis
Can floating tablets made from liquorice extract effectively treat Helicobacter pylori and gastric ulcers?
Conclusion
The optimized floating tablet formulation released 98.3% of the drug in 8 hours and had a buoyancy time of 3.5 minutes.
Supporting Evidence
- The tablets showed good physical properties and met USP requirements.
- The formulation F6 was optimized for drug release and buoyancy.
- The study demonstrated that the floating tablets can improve drug delivery in the stomach.
Takeaway
Researchers made special tablets that float in the stomach to help deliver medicine for stomach problems. These tablets worked well and released most of the medicine over 8 hours.
Methodology
The tablets were made using direct compression with ingredients like liquorice extract, HPMC K100M, and sodium bicarbonate, and were tested for various physical parameters.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website