MLPAinter: A Tool for Analyzing MLPA Data
Author Information
Author(s): Ronald van Eijk, Paul HC Eilers, Remco Natté, Anne-Marie Cleton-Jansen, Hans Morreau, Tom van Wezel, Jan Oosting
Primary Institution: Leiden University Medical Center
Hypothesis
Can we develop a software tool to improve the analysis and management of MLPA data?
Conclusion
MLPAinter streamlines the handling of MLPA data, ensuring efficient data flow from experiment initiation to report generation.
Supporting Evidence
- MLPA allows for the analysis of up to 50 genomic sequences in one experiment.
- The software integrates data management, normalization, and visualization.
- MLPAinter has been used successfully for over two years in managing over 3000 samples.
Takeaway
MLPAinter is a computer program that helps scientists analyze DNA data quickly and easily, making it simpler to find genetic changes.
Methodology
Developed a relational database and a Delphi front-end for managing MLPA data, including normalization and visualization.
Limitations
The system currently does not fully integrate all information generated during an experiment.
Digital Object Identifier (DOI)
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