Non-Hodgkin's Lymphoma of the Sphenoid Sinus and Oculomotor Nerve Palsy
Author Information
Author(s): Park Young Mok, Cho Jun Hyung, Cho Jae Yong, Huh Ji Soon, Ahn Jung Yong
Primary Institution: Yonsei University College of Medicine
Hypothesis
Can non-Hodgkin's lymphoma of the sphenoid sinus present with isolated oculomotor nerve palsy?
Conclusion
Non-Hodgkin's lymphoma of the sphenoid sinus can present with isolated oculomotor nerve palsy, which may resolve dramatically after chemotherapy.
Supporting Evidence
- Isolated oculomotor nerve palsy is a rare initial presentation of malignant tumors of the sphenoid sinus.
- The patient had a three-month history of headache and diplopia.
- Following six cycles of chemotherapy, the oculomotor nerve palsy was completely resolved.
Takeaway
A woman had a rare type of cancer in her sphenoid sinus that caused her eye to not move properly, but after treatment, her eye movement got better.
Methodology
The patient underwent transsphenoidal biopsy and received chemotherapy consisting of eight cycles of CHOP with adjuvant Rituximab.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
53-year-old woman with no significant past medical history.
Digital Object Identifier (DOI)
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