Biofilm on Cochlear Implants: A Systematic Review
Author Information
Author(s): Tsikopoulos Alexios, Tsikopoulos Konstantinos, Sidiropoulos Konstantinos, Meroni Gabriele, Triaridis Stefanos, Drago Lorenzo, Papaioannidou Paraskevi
Primary Institution: Aristotle University of Thessaloniki
Hypothesis
What are the development and prevention methods for biofilm formation on cochlear implants?
Conclusion
Biofilm formation on cochlear implants is a significant complication that often requires explantation, with various experimental prevention methods showing promising antibiofilm activity.
Supporting Evidence
- Biofilms in cochlear implants are usually localized in recesses like the removable magnet pocket.
- S. aureus and P. aeruginosa are the most commonly isolated microorganisms associated with biofilm formation.
- Most examined biofilm prevention methods showed sufficient antibiofilm activity.
- Explantation is often required for biofilm-infected cochlear implants.
Takeaway
Biofilms can grow on cochlear implants, making them hard to treat, and sometimes the only solution is to remove the implant. Researchers are looking for better ways to stop this from happening.
Methodology
A systematic search of literature published in PubMed, Scopus, and ScienceDirect was conducted to evaluate biofilm formation and prevention strategies on cochlear implants.
Potential Biases
Some studies lacked detailed reporting on sample size and randomization, which could introduce bias.
Limitations
Most studies were in vitro or animal studies, which may not fully represent human outcomes.
Participant Demographics
Included studies involved both pediatric and adult patients with cochlear implants.
Digital Object Identifier (DOI)
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