4-(3,4-Diacetyl-5-methyl-1H-pyrazol-1-yl)benzenesulfonamide
2011
Study of a New Compound with Antitumor Activity
publication
Author Information
Author(s): Abdel-Aziz Hatem A., Bari Ahmed, Ng Seik Weng
Primary Institution: King Saud University
Hypothesis
The new aryl-pyrazole compound with a sulfonamide substituent will improve aqueous solubility and exhibit antitumor activity.
Conclusion
The synthesized compound forms a three-dimensional network in the crystal structure and is expected to have improved solubility.
Supporting Evidence
- The compound has a sulfonamide group that may enhance its solubility.
- The crystal structure shows a three-dimensional network formed by hydrogen bonding.
Takeaway
Scientists made a new chemical that might help fight cancer better because it can dissolve in water more easily.
Methodology
The compound was synthesized through a cycloaddition reaction under microwave conditions.
Digital Object Identifier (DOI)
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