Efficacy and safety of office-based diode laser ablation for recurrent low-grade non-muscle-invasive bladder cancer under local anaesthesia: A pilot study
2024

Diode Laser Ablation for Bladder Cancer

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): I. A. Khalil, Younes Nagy, Badawi Alaeddin, Al Rumaihi Khalid

Primary Institution: Hamad Medical Corporation, Doha, Qatar

Hypothesis

This study aims to assess the efficacy and safety of office-based diode laser ablation for treating recurrent low-grade non-muscle-invasive bladder cancer under local anesthesia.

Conclusion

Office-based diode laser ablation is a safe, effective, and well-tolerated alternative for treating recurrent low-grade NMIBC with a low volume, less than 1 cm, under local anesthesia.

Supporting Evidence

  • The recurrence rate post-ablation for the entire cohort was 70%.
  • Patients tolerated the procedure well, reporting only mild pain.
  • There were no complications greater than grade 1 on the Clavien-Dindo classification.

Takeaway

Doctors can use a special laser to treat bladder cancer in a way that is safe and doesn't hurt too much, helping patients avoid more serious surgeries.

Methodology

A retrospective analysis was conducted on patients with recurrent low-grade NMIBC who underwent office-based diode transurethral laser ablation under local anesthesia.

Limitations

The study is retrospective with a small sample size.

Participant Demographics

Mean age of participants was 55 years, with a male-to-female ratio of 3.2:1.

Statistical Information

P-Value

0.046

Statistical Significance

p=0.046

Digital Object Identifier (DOI)

10.1080/20905998.2024.2381816

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