Engineering Out the Risk for Infection with Urinary Catheters
2001

Preventing Catheter-Associated Urinary Tract Infections

Sample size: 850 publication Evidence: moderate

Author Information

Author(s): Dennis G. Maki, Paul A. Tambyah

Primary Institution: University of Wisconsin Medical School

Hypothesis

Novel urinary catheters with antiinfective properties can reduce the risk of catheter-associated urinary tract infections (CAUTIs).

Conclusion

Using silver-hydrogel catheters significantly reduces the incidence of CAUTIs, particularly those caused by gram-positive organisms.

Supporting Evidence

  • CAUTIs are the most common nosocomial infection, comprising over 40% of all institutionally acquired infections.
  • Patients with CAUTI have an increased institutional death rate unrelated to urosepsis.
  • Silver-hydrogel catheters reduced CAUTI incidence by 26% compared to standard catheters.

Takeaway

Doctors are trying to make catheters safer so that fewer people get infections. A new type of catheter helps keep people from getting sick.

Methodology

A double-blinded trial was conducted with 850 patients to compare the effectiveness of silver-hydrogel catheters against standard catheters in preventing CAUTIs.

Potential Biases

Potential bias in the selection of patients and the small sample sizes in some studies may affect the reliability of the results.

Limitations

The studies on medicated catheters were small, and the long-term effects of using these catheters on antibiotic resistance were not fully resolved.

Participant Demographics

Patients in U.S. acute-care hospitals requiring catheterization.

Statistical Information

P-Value

0.04

Statistical Significance

p=0.04

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