Successful Control of Myasthenic Crisis After the Introduction of Ravulizumab in Myasthenia Gravis: A Case Report
2024

Successful Control of Myasthenic Crisis with Ravulizumab

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Uchi Takafumi, Konno Shingo, Kihara Hideo, Sugimoto Hideki

Primary Institution: Toho University Ohashi Medical Center

Hypothesis

Can ravulizumab effectively manage a myasthenic crisis in patients with myasthenia gravis?

Conclusion

Ravulizumab was effective in improving respiratory function and enabling ventilator weaning in a patient with a myasthenic crisis.

Supporting Evidence

  • This case is the first report of successful weaning from mechanical ventilation after treatment with ravulizumab in a patient with a myasthenic crisis.
  • Ravulizumab improved the patient's respiratory function, allowing for hospital discharge.
  • The patient had previously received multiple treatments without success before ravulizumab was introduced.

Takeaway

A 71-year-old woman with a severe muscle weakness condition got better after receiving a new medicine called ravulizumab, which helped her breathe again.

Methodology

This case study involved a 71-year-old woman treated with ravulizumab after experiencing a myasthenic crisis.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

71-year-old woman with a history of complicated type 1 diabetes.

Digital Object Identifier (DOI)

10.7759/cureus.74117

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