MEDIATING ROLE OF DEPRESSION IN THE ASSOCIATION BETWEEN CUMULATIVE LONELINESS AND MEMORY FUNCTION, 2006–2020
2024

Loneliness, Depression, and Memory in Older Adults

Sample size: 4764 publication Evidence: moderate

Author Information

Author(s): Yu Xuexin, Zahodne Laura, Gross Alden, Needham Belinda, Langa Kenneth, Kobayashi Lindsay

Primary Institution: University of Michigan

Hypothesis

Depressive symptoms mediate the relationship between cumulative loneliness and memory function in older adults.

Conclusion

Cumulative loneliness negatively impacts memory function, and this effect is mediated by depressive symptoms.

Supporting Evidence

  • Greater cumulative loneliness was linked to lower memory function.
  • Depressive symptoms mediated the relationship between loneliness and memory.

Takeaway

Feeling lonely can make it harder to remember things, and being sad about it makes it even worse.

Methodology

Data were analyzed from two cohorts of adults aged 50+ using the UCLA Loneliness Scale and the Center for Epidemiologic Studies Depression Scale.

Participant Demographics

Mean age was 65 years, with 62% female.

Statistical Information

Confidence Interval

95% CI: -0.016 to -0.002

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0285

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