Immune-related adverse events with renal colic as the main manifestation: a case report of sintilimab-induced ureteritis/cystitis treated by ureteral stent and review of the literature
2024

Sintilimab-Induced Ureteritis/Cystitis Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Ji Jiaxiang, Lai Chin-Hui, Zhang Xiaowei, Hu Hao

Primary Institution: Peking University People’s Hospital, Beijing, China

Hypothesis

Can ureteral stenting effectively treat sintilimab-induced ureteritis/cystitis without corticosteroids?

Conclusion

Ureteral stenting can effectively relieve symptoms of sintilimab-induced ureteritis/cystitis without the use of corticosteroids.

Supporting Evidence

  • Ureteral stenting resolved the patient's severe renal colic immediately.
  • The patient had significant tumor regression post-surgery.
  • Previous treatments with antibiotics and NSAIDs were ineffective.

Takeaway

A patient with severe kidney pain from a cancer treatment had a special tube put in to help drain urine, which made him feel better without using strong medicines.

Methodology

The patient was treated with ureteral stenting after failing to respond to other medications.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

55-year-old male with gastric cancer.

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1501415

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