Managing Bladder Cancer After Organ Transplantation
Author Information
Author(s): Jeffrey J. Tomaszewski, Jeffrey A. Larson, Marc C. Smaldone, Matthew H. Hayn, Stephen V. Jackman
Primary Institution: University of Pittsburgh
Hypothesis
What is the experience of managing bladder cancer in patients following liver and renal transplantation?
Conclusion
Bladder cancer is rare after organ transplantation but can be effectively managed with appropriate therapies.
Supporting Evidence
- Bladder cancer was diagnosed in 11 out of 5,686 transplant recipients, indicating a low incidence.
- Patients treated with TURBT and BCG therapy had no recurrence at a mean follow-up of 51 months.
- Radical cystectomy was performed on one patient with high-grade BUC, who remains disease-free after 98 months.
Takeaway
This study looked at how doctors treat bladder cancer in people who have had kidney or liver transplants. They found that even though it's not common, it can be treated successfully.
Methodology
Retrospective review of patients diagnosed with bladder urothelial carcinoma following solid organ transplantation.
Potential Biases
Reporting bias may have occurred in the early years of the study.
Limitations
The study is limited by sample size and retrospective design.
Participant Demographics
All patients were male, with a mean age of 62 years at transplantation.
Digital Object Identifier (DOI)
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