Metabolic Profiling of CSF: Evidence that Early Intervention May Impact on Disease Progression and Outcome in Schizophrenia
2006

Metabolic Profiling of CSF in Schizophrenia

publication

Author Information

Author(s): Dave Hambridge

Hypothesis

Early intervention may impact disease progression and outcome in schizophrenia.

Conclusion

The study suggests that metabolic profiling of cerebrospinal fluid could help in understanding and potentially improving outcomes in schizophrenia.

Supporting Evidence

  • The study is based on relatively small subgroups of patients.
  • Patients had DSM-IV–diagnosed schizophrenia, which excludes organic causation.

Takeaway

This study looks at how testing the fluid around the brain might help doctors treat schizophrenia better.

Limitations

The study is based on relatively small subgroups of patients.

Participant Demographics

Patients diagnosed with DSM-IV schizophrenia.

Digital Object Identifier (DOI)

10.1371/journal.pmed.0030327

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