Aromatase Inhibitors in Men: Effects and Therapeutic Options
Author Information
Author(s): de Ronde Willem, de Jong Frank H
Primary Institution: Department of Internal Medicine, Kennemer Gasthuis, The Netherlands; Department of Internal Medicine, Erasmus University Medical Center, The Netherlands
Hypothesis
Aromatase inhibitors may be used to increase adult height in boys with certain conditions.
Conclusion
Aromatase inhibitors can delay epiphysial maturation in boys and improve testosterone levels in adult men, but their long-term efficacy and safety in males are not yet established.
Supporting Evidence
- Aromatase inhibitors effectively delay epiphysial maturation in boys.
- They improve testosterone levels in adult men.
- Long-term safety of aromatase inhibitors in males is not yet established.
Takeaway
Aromatase inhibitors can help boys grow taller by slowing down their bone growth, and they can also help men with low testosterone levels, but we need to be careful about their long-term effects.
Methodology
This review discusses the potential targets and evidence for the use of aromatase inhibitors in men, including their effects on testosterone levels and bone maturation.
Limitations
The long-term efficacy and safety of aromatase inhibitors in males have not yet been established.
Digital Object Identifier (DOI)
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