Comparing FFR and Non-Invasive Tests for Heart Ischaemia
Author Information
Author(s): Fairbairn Timothy A, Mather Adam, Greenwood John, Plein Sven
Primary Institution: University of Leeds
Hypothesis
How does Fractional Flow Reserve (FFR) compare with non-invasive tests in assessing ischaemia due to intermediate coronary artery stenosis?
Conclusion
Non-invasive imaging does not correlate well with FFR measurements in intermediate coronary lesions.
Supporting Evidence
- FFR was classified negative in 20 out of 33 measurements.
- Perfusion-CMR detected ischaemia in 3 vessels.
- SPECT also detected ischaemia in 3 vessels.
- Coronary stenosis by QCA and FFR correlated poorly.
Takeaway
Doctors used a special test called FFR to check heart problems, but it didn't match well with other tests that are easier to do.
Methodology
Patients with chest pain underwent SPECT, perfusion-CMR, and coronary angiography to assess FFR.
Limitations
The study had a small sample size and poor correlation between FFR and non-invasive imaging.
Participant Demographics
Average age 57, 78% male.
Statistical Information
P-Value
0.054
Statistical Significance
p=0.054
Digital Object Identifier (DOI)
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