Breast self-examination and death from breast cancer: a meta-analysis
2003

Breast Self-Examination and Breast Cancer Deaths

Sample size: 580000 publication 10 minutes Evidence: high

Author Information

Author(s): Hackshaw A K, Paul E A

Primary Institution: Barts & The London School of Medicine & Dentistry, Queen Mary, University of London

Hypothesis

Does practicing breast self-examination reduce mortality from breast cancer?

Conclusion

The study found no significant evidence that breast self-examination reduces breast cancer mortality.

Supporting Evidence

  • Women who practiced breast self-examination had a 36% reduction in the risk of death from breast cancer.
  • Randomized trials showed no effect of breast self-examination on breast cancer mortality.
  • Women taught breast self-examination were more likely to seek medical advice after finding a lump.

Takeaway

Teaching women to check their breasts regularly doesn't help them live longer if they get breast cancer.

Methodology

A meta-analysis of observational studies and randomized trials on breast self-examination and breast cancer mortality.

Potential Biases

Potential biases include publication bias, selection bias, recall bias, lead-time bias, and length-biased sampling.

Limitations

The studies may be affected by biases such as selection bias and recall bias.

Participant Demographics

Women aged 30-69, with varying socioeconomic statuses.

Statistical Information

P-Value

<0.001

Confidence Interval

0.56–0.73

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600847

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication