Using Autologous Cultured Fibroblasts to Treat Wrinkles and Scars
Author Information
Author(s): Nilforoushzadeh Mohammad Ali, Siadat Amir Hossein, Arianrad Mojgan, Moulavi Fariba, Baradaran Elahe Haft, Esfahani Mohhamad Hossein Nasr
Primary Institution: Isfahan University of Medical Sciences
Hypothesis
Can autologous cultured fibroblasts effectively treat facial wrinkles and atrophic scars?
Conclusion
Autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.
Supporting Evidence
- 85% of the participants were female.
- The mean improvement at 6 months was 41%.
- No serious side effects were reported, only minor reddening.
- Fibroblast injections showed increased collagen formation.
- Results suggest long-lasting improvements from fibroblast injections.
Takeaway
Doctors took some skin from patients and grew special cells to help fix wrinkles and scars, and it worked well for most people.
Methodology
20 patients received autologous cultured fibroblast injections in the nasolabial fold, with follow-ups at 6 months to assess improvement.
Limitations
The degree of improvement varied between individuals, and longer follow-up studies are needed.
Participant Demographics
85% female and 15% male, ages 40 to 62.
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