Study on Oesophageal Adenocarcinoma in Women
Author Information
Author(s): Cheng K K, Sharp L, McKinney P A, Logan R F A, Chilvers C E D, Cook-Mozaffari P, Ahmed A, Day N E
Primary Institution: Department of Public Health and Epidemiology, The University of Birmingham
Hypothesis
What are the risk factors for oesophageal adenocarcinoma in women?
Conclusion
High body mass index and low fruit consumption are significant risk factors for oesophageal adenocarcinoma in women, while breastfeeding may reduce the risk.
Supporting Evidence
- High BMI around age 20 is linked to increased risk of oesophageal adenocarcinoma.
- Low fruit consumption is associated with higher risk of this cancer.
- Breastfeeding may reduce the risk of developing oesophageal adenocarcinoma.
Takeaway
Being overweight when you are young and not eating enough fruit can increase the chances of getting a certain type of throat cancer, but breastfeeding might help protect against it.
Methodology
Multi-centre, population-based case-control study in four regions in England and Scotland.
Participant Demographics
74 women with adenocarcinoma and 74 matched female controls.
Statistical Information
Confidence Interval
95% CI 1.28–28.52 for BMI; 95% CI 0.01–0.49 for fruit consumption; 95% CI 0.20–0.82 for breastfeeding.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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