Effects of Bifidobacterium on Obesity in Rats
Author Information
Author(s): An Hyang Mi, Park Shin Young, Lee Do Kyung, Kim Jung Rae, Cha Min Kyeong, Lee Si Won, Lim Hyung Taeck, Kim Kyung Jae, Ha Nam Joo
Primary Institution: Sahmyook University
Hypothesis
The study aims to assess the antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats.
Conclusion
Bifidobacterium spp. may have beneficial antiobesity effects.
Supporting Evidence
- The LAB reduced body and fat weights in the rats.
- Blood serum levels of cholesterol and triglycerides were significantly decreased in the LAB group.
- Fecal LAB counts significantly increased in the HFD-LAB group compared to the HFD group.
- Harmful enzyme activities were significantly decreased in the HFD-LAB group.
Takeaway
This study found that giving certain probiotics to rats on a high-fat diet helped them lose weight and lower their fat levels.
Methodology
Thirty-six male Sprague-Dawley rats were divided into three groups and fed different diets for 7 weeks, after which various health metrics were measured.
Limitations
The study was conducted on rats, and results may not directly translate to humans.
Participant Demographics
Male Sprague-Dawley rats, aged three weeks at the start of the study.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website