Safety of electroconvulsive therapy in the context of physiological and medical complexity: A state‐of‐the art review
2025

Safety of Electroconvulsive Therapy in Complex Medical Conditions

Sample size: 124 publication Evidence: moderate

Author Information

Author(s): Elias Alby MD, FRANZCP, PhD, Das Soumitra MD, FRANZCP, MPH, Kirkland James MBBS, Loyal Sarabjit M (MED), FRANZCP, Thomas Naveen DPM, MD, DNB, FRANZCP

Primary Institution: The University of Melbourne

Hypothesis

This review aimed to evaluate the literature on physiological and medical complexities during ECT and discuss risk mitigation strategies.

Conclusion

Overall, ECT remains a relatively safe treatment even in the presence of medical and physiological complexities.

Supporting Evidence

  • Mortality directly attributed to ECT is extremely rare.
  • Certain medical conditions may indicate a high risk for ECT.
  • Risks can be mitigated with safety protocols and collaboration with specialists.

Takeaway

Electroconvulsive therapy (ECT) is generally safe, even for people with complicated medical issues, but doctors need to be careful and follow safety guidelines.

Methodology

The literature search was conducted using keywords related to ECT, contraindications, and medical precautions, with a focus on recent advancements and emerging trends.

Potential Biases

The review is biased toward a nonsystematic selection of literature without a specific protocol.

Limitations

The results are based on limited evidence from case reports and retrospective reviews, which may not capture all serious outcomes.

Digital Object Identifier (DOI)

10.1002/pcn5.70051

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