2-Methoxy-4-[(4-methylpiperazin-1-yl)iminomethyl]phenol
2011
Study of a New Compound Derived from Piperazine
publication
Evidence: moderate
Author Information
Author(s): Zhou Li-Na, Yan Long, Zhou Hui-Liang, Yang Qing-Feng, Hu Qi-Lin
Primary Institution: Ningxia University
Hypothesis
The study investigates the structure and properties of a new hydrazone compound formed from 4-hydroxy-3-methoxy-benzaldehyde and 1-amino-4-methylpiperazine.
Conclusion
The compound exhibits a chair conformation in the piperazine ring and is stabilized by various hydrogen bonds in its crystal structure.
Supporting Evidence
- The compound was synthesized with an 80% yield.
- The piperazine ring adopts a chair conformation.
- Strong intermolecular hydrogen bonds contribute to the crystal packing.
Takeaway
Scientists made a new chemical compound by mixing two ingredients, and they found that it has a special shape and sticks together well.
Methodology
The compound was synthesized through a solvent-free reaction and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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