Impact of board-certified intensive care training facilities on choice of adjunctive therapies and prognosis of severe respiratory failure: a nationwide cohort study
2024

Impact of Intensive Care Training Facilities on Severe Respiratory Failure Outcomes

Sample size: 66905 publication 10 minutes Evidence: high

Author Information

Author(s): Yoshida Takuo, Shimizu Sayuri, Fushimi Kiyohide, Mihara Takahiro

Primary Institution: Yokohama City University

Hypothesis

What is the impact of board-certified intensive care training facilities on treatment choices and patient outcomes for severe respiratory failure?

Conclusion

Board-certified intensive care training facilities were associated with lower in-hospital mortality compared to non-certified facilities.

Supporting Evidence

  • Board-certified facilities had lower in-hospital mortality rates (31% vs. 38%).
  • Patients in board-certified facilities received more adjunctive therapies.
  • Older patients benefited more from treatment in board-certified facilities.
  • Board-certified facilities had higher rates of ICU admissions (74% vs. 30%).
  • Subgroup analyses showed greater benefits for patients requiring vasopressors.

Takeaway

Hospitals with special training for intensive care doctors help patients with severe breathing problems do better than those without such training.

Methodology

This retrospective cohort study used Japan’s nationwide in-patient database from 2016 to 2019, comparing treatments and in-hospital mortality between board-certified and non-certified facilities.

Potential Biases

Potential for unmeasured confounding factors affecting the outcomes.

Limitations

The study is observational, and residual confounding factors may exist; it also lacks data on certain clinical practices.

Participant Demographics

Patients with severe respiratory failure requiring mechanical ventilation, with a mean age of 75 years.

Statistical Information

P-Value

0.75

Confidence Interval

0.72–0.77

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/s40560-024-00766-8

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