Prevalence of Non-Viral Bloodborne Pathogens Among Healthy Blood Donors in Western Mexico: Problems and Failures of Public Health Policy
2024

Prevalence of Non-Viral Bloodborne Pathogens Among Healthy Blood Donors in Western Mexico

Sample size: 228328 publication 10 minutes Evidence: moderate

Author Information

Author(s): Guerrero-García José de Jesús, Flores-González Alejandra, Sánchez-Sánchez Alma Marina, Magaña-Duarte Rafael, Mireles-Ramírez Mario Alberto, Ortiz-Lazareno Pablo Cesar, Sierra Díaz Erick, Ortuño-Sahagún Daniel

Primary Institution: Banco de Sangre Central, Unidad Médica de Alta Especialidad (UMAE), Hospital de Especialidades, Instituto Mexicano del Seguro Social (IMSS)

Hypothesis

What is the prevalence of non-viral bloodborne diseases in blood donors in Western Mexico?

Conclusion

The study found a prevalence of 299 non-viral bloodborne diseases per 100,000 blood donors, indicating a need for improved public health policies.

Supporting Evidence

  • 682 positive cases of non-viral bloodborne diseases were confirmed among 228,328 donors.
  • The overall prevalence for non-viral bloodborne diseases was 299 per 100,000 blood donors.
  • Prevalence for syphilis was 209 per 100,000, for Chagas disease was 36 per 100,000, and for brucellosis was 53 per 100,000.
  • Only 34.4% of reactive donors completed their follow-up testing.

Takeaway

This study looked at healthy blood donors in Mexico and found that some have infections that can be spread through blood, which means we need to be more careful about blood safety.

Methodology

A cross-sectional study was conducted using the blood bank database from 2018 to 2023, analyzing seroreactive blood donors for non-viral pathogens.

Potential Biases

Some donors provided incorrect personal information, making follow-up challenging.

Limitations

Not all reactive donors completed follow-up testing, leading to potential underestimation of prevalence.

Participant Demographics

The mean age of donors was 33.84 years, with 64.32% being men.

Statistical Information

P-Value

0.299

Confidence Interval

95% CI 277–322

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/pathogens13121027

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