Ciprofloxacin Resistance in Neisseria meningitidis, France
2008

Ciprofloxacin Resistance in Neisseria meningitidis in France

Sample size: 5146 publication Evidence: moderate

Author Information

Author(s): Skoczynska Anna, Alonso Jean-Michel, Taha Muhamed-Kheir

Primary Institution: Institut Pasteur, Paris, France

Hypothesis

What is the prevalence of ciprofloxacin resistance in Neisseria meningitidis isolates in France?

Conclusion

Ciprofloxacin resistance in Neisseria meningitidis is rare in France, with only three resistant isolates identified among thousands screened.

Supporting Evidence

  • Only three ciprofloxacin-resistant isolates were found among over 5,000 tested.
  • Resistance was identified in isolates from cases of invasive disease.
  • Two resistant isolates were linked to different sequence types.

Takeaway

Doctors found very few cases of Neisseria meningitidis that are resistant to ciprofloxacin in France, which is good news for treating infections.

Methodology

Clinical N. meningitidis isolates were screened for ciprofloxacin resistance at the French National Reference Center for Meningococci.

Limitations

The low number of African isolates tested may not represent the overall resistance situation.

Participant Demographics

Isolates included 4,900 from France and 246 from various African countries.

Digital Object Identifier (DOI)

10.3201/eid1408.080040

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