Splanchnic Vein Thrombosis in Children in the Mediterranean Area
Author Information
Author(s): Hanaa El-Karaksy, Mona El-Raziky
Primary Institution: Cairo University
Hypothesis
What are the risk factors and prevalence of splanchnic vein thrombosis in children from the South Mediterranean area?
Conclusion
Hereditary thrombophilia is common in children with portal vein thrombosis, with the most frequent mutation being factor V Leiden.
Supporting Evidence
- 30% of children with portal vein thrombosis had circumstantial risk factors.
- 62.5% of children with portal vein thrombosis had hereditary thrombophilia.
- Factor V Leiden mutation was found in 30% of the children studied.
- Concurrence of more than one hereditary thrombophilia was noted in 12.5% of cases.
Takeaway
This study looks at blood clots in children's stomach veins and finds that some kids have a genetic reason for these clots.
Methodology
The study analyzed 40 children with extrahepatic portal vein obstruction for hereditary thrombophilia and circumstantial risk factors.
Potential Biases
Potential bias due to reliance on local medical journals that are difficult to access.
Limitations
Data from the South Mediterranean area are deficient and may not represent the entire population.
Participant Demographics
Mean age of participants was 9.4 years, with a male to female ratio of 2.1:1.
Statistical Information
P-Value
0.03
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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