Fructooligosaccharides for Relieving Functional Constipation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
2024

Fructooligosaccharides for Relieving Functional Constipation

Sample size: 713 publication 10 minutes Evidence: moderate

Author Information

Author(s): Zhen Hongmin, Qian Hanwei, Liu Xiaoyan, Tan Chen

Primary Institution: Beijing Technology and Business University

Hypothesis

Can fructooligosaccharides (FOS) improve bowel movement frequency and stool consistency in individuals with functional constipation?

Conclusion

Fructooligosaccharides may enhance bowel movement frequency and stool consistency, suggesting they could be a useful dietary treatment for constipation.

Supporting Evidence

  • FOS significantly increased bowel movement frequency in participants.
  • FOS improved stool consistency, making stools softer.
  • Participants reported reduced straining effort and pain during defecation.
  • Some participants experienced mild bloating as a side effect of FOS.

Takeaway

Eating fructooligosaccharides can help people poop more often and make their poop softer, which is good for constipation.

Methodology

A systematic review and meta-analysis of 17 randomized controlled trials assessing the effects of FOS on bowel function.

Potential Biases

The risk of bias was primarily attributed to selection bias, attrition bias, and reporting bias.

Limitations

The study highlights the need for further research to determine optimal dosages and the variability in individual responses to FOS.

Participant Demographics

Participants included both healthy individuals and those with constipation, ranging from infants to seniors.

Statistical Information

P-Value

p<0.00001

Confidence Interval

95% CI: 0.80, 1.50

Statistical Significance

p<0.00001

Digital Object Identifier (DOI)

10.3390/foods13243993

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