Changes induced by dietary energy intake and divergent selection for muscle fat content in rainbow trout (Oncorhynchus mykiss), assessed by transcriptome and proteome analysis of the liver
2008

Diet and Genetic Selection Effects on Rainbow Trout Liver Metabolism

Sample size: 57 publication 10 minutes Evidence: high

Author Information

Author(s): Kolditz Catherine-Ines, Paboeuf Gilles, Borthaire Maïena, Esquerré Diane, SanCristobal Magali, Lefèvre Florence, Médale Françoise

Primary Institution: INRA

Hypothesis

How do dietary energy intake and genetic selection for muscle fat content affect liver metabolism in rainbow trout?

Conclusion

The study identified novel genes and proteins that respond to high energy diets, revealing significant effects on liver metabolism related to muscle fat content.

Supporting Evidence

  • The study found that a high energy diet reduced the expression of genes involved in lipid metabolism.
  • Transcripts related to amino acid catabolism were higher in the fatty muscle line compared to the lean muscle line.
  • Proteins involved in antioxidant metabolism were affected by dietary treatments.

Takeaway

This study looked at how different diets and breeding choices affect the way rainbow trout store fat in their bodies, especially in their livers.

Methodology

The study used transcriptome and proteome analyses to assess liver changes in rainbow trout fed different energy diets and selected for muscle fat content.

Limitations

The study primarily focused on liver metabolism and may not fully represent other metabolic processes in the fish.

Participant Demographics

Rainbow trout of two genetic lines (lean and fatty muscle lines) were used.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2164-9-506

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