DOES COGNITIVE RESERVE MODERATE THE RELATIONSHIP BETWEEN STROKE SEVERITY AND COGNITIVE FUNCTION?
2024

Cognitive Reserve and Stroke Impact on Cognitive Function

Sample size: 371 publication Evidence: moderate

Author Information

Author(s): Ou Yinuo, Lv Yalin, Wei Hui, Zhang Yanrong, Li Juan

Primary Institution: Huashan Hospital Fudan University

Hypothesis

Does cognitive reserve moderate the relationship between stroke severity and cognitive function?

Conclusion

Cognitive reserve can mitigate the impact of stroke burden on long-term cognitive decline in Chinese AIS patients.

Supporting Evidence

  • Cognitive function improved over time in all patients after stroke.
  • Patients with higher NIHSS scores had worse cognitive function.
  • Patients with a higher level of cognitive reserve had better cognitive function after stroke.

Takeaway

After a stroke, people with a higher cognitive reserve do better in thinking skills than those with a lower cognitive reserve.

Methodology

A longitudinal survey of patients with acute ischemic stroke was conducted, assessing stroke severity, cognitive reserve, and cognitive function at multiple time points.

Participant Demographics

Patients with acute ischemic stroke from four stroke centers in Nanjing and Shanghai, China.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/geroni/igae098.1013

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