Next Generation Sequencing Provides Rapid Access to the Genome of Puccinia striiformis f. sp. tritici, the Causal Agent of Wheat Stripe Rust
2011

Genome of Wheat Stripe Rust Fungus Revealed

publication Evidence: high

Author Information

Author(s): Dario Cantu, Manjula Govindarajulu, Alex Kozik, Meinan Wang, Xianming Chen, Kenji K. Kojima, Jerzy Jurka, Richard W. Michelmore, Jorge Dubcovsky

Primary Institution: University of California Davis

Hypothesis

Next Generation Sequencing can provide rapid access to the genome of Puccinia striiformis f. sp. tritici.

Conclusion

The assembly of the PST-130 genome provides valuable resources for identifying and cloning PST genes and their regulatory regions.

Supporting Evidence

  • The genome assembly provides an estimated coverage of at least 88% of the PST genes.
  • Comparative genomics approaches were used to improve gene annotation.
  • Over 140 families of transposable elements were identified in the PST-130 genome.

Takeaway

Scientists sequenced the genome of a fungus that causes wheat stripe rust, which helps in understanding how to fight this disease.

Methodology

Illumina sequencing was used to obtain nearly 80 million high-quality paired-end reads, which were assembled into contigs.

Limitations

The automatic gene prediction has limitations and requires further curation.

Digital Object Identifier (DOI)

10.1371/journal.pone.0024230

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