Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
2001
Detecting ERβ in Breast Cancer
publication
Author Information
Author(s): Skliris G P, Carder P J, Lansdown M R J, Speirs V
Primary Institution: Molecular Medicine Unit, University of Leeds, St James's University Hospital
Hypothesis
What is the significance of ERβ protein expression in breast cancer?
Conclusion
This study demonstrates the immunohistochemical detection of ERβ in archival breast tumors for the first time.
Supporting Evidence
- ERβ is a second estrogen receptor that has been less studied than the first.
- Most previous studies focused on mRNA levels rather than protein expression.
Takeaway
Researchers found a way to see a specific protein in breast cancer samples, which could help understand the disease better.
Methodology
Immunohistochemical detection of ERβ in archival breast tumors.
Digital Object Identifier (DOI)
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