Shewanella oneidensis: a new and efficient System for Expression and Maturation of heterologous [Fe-Fe] Hydrogenase from Chlamydomonas reinhardtii
2008

Using Shewanella oneidensis to Produce Hydrogen from Algal Enzyme

Sample size: 1 publication Evidence: moderate

Author Information

Author(s): Sybirna Kateryna, Antoine Tatiana, Lindberg Pia, Fourmond Vincent, Rousset Marc, Méjean Vincent, Bottin Hervé

Primary Institution: CEA, DSV, iBiTec-S, SB2SM, LPB (URA CNRS 2096), Gif-sur-Yvette cedex, France

Hypothesis

Can Shewanella oneidensis serve as an efficient system for the expression and maturation of the [Fe-Fe] hydrogenase from Chlamydomonas reinhardtii?

Conclusion

The study developed an efficient system for the heterologous expression and maturation of the hydrogenase from Chlamydomonas reinhardtii using Shewanella oneidensis.

Supporting Evidence

  • Hydrogen formation by S. oneidensis was significantly increased when grown with specific substrates.
  • The system produced 0.4 – 0.5 mg l-1 of catalytically active HydA1.
  • HydA1 contained six iron atoms per molecule of protein, confirming its maturation.

Takeaway

Scientists found a new way to make a special enzyme that helps produce hydrogen using a type of bacteria, which is better than previous methods.

Methodology

The study involved using Shewanella oneidensis to express and purify the hydrogenase from Chlamydomonas reinhardtii under anaerobic conditions with various substrates.

Digital Object Identifier (DOI)

10.1186/1472-6750-8-73

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