Forest Fragmentation as Cause of Bacterial Transmission among Nonhuman Primates, Humans, and Livestock, Uganda
2008

Forest Fragmentation and Bacterial Transmission

Sample size: 252 publication Evidence: high

Author Information

Author(s): Tony L. Goldberg, Thomas R. Gillespie, Innocent B. Rwego, Elizabeth L. Estoff, Colin A. Chapman

Primary Institution: University of Illinois, Urbana, Illinois, USA

Hypothesis

Forest fragmentation increases bacterial transmission among nonhuman primates, humans, and livestock.

Conclusion

Forest fragmentation increases bacterial transmission between primates and humans and their livestock.

Supporting Evidence

  • Humans living near forest fragments had bacteria 75% more similar to those from primates in those fragments.
  • Genetic similarity between human/livestock and primate bacteria increased 3-fold with higher anthropogenic disturbance.
  • Bacteria from humans and livestock were twice as similar to those of red-tailed guenons than to other primate species.
  • Tending livestock and experiencing gastrointestinal symptoms increased genetic similarity between participant’s bacteria and those of nearby primates.

Takeaway

When forests are cut down, bacteria can spread more easily between animals and people living nearby.

Methodology

The study involved collecting fecal samples from humans, livestock, and primates to analyze genetic relationships among E. coli isolates.

Potential Biases

Potential response biases during surveys due to the presence of researchers.

Limitations

The study may not account for all factors influencing bacterial transmission, and results may differ for more virulent pathogens.

Participant Demographics

Participants included 252 individuals, with 48% male and 52% female, ranging in age from 2 months to 77 years.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3201/eid1409.071196

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