MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
1999
Discovery of a New Transporter Related to Drug Resistance
publication
Author Information
Author(s): Belinsky M G, Kruh G D
Primary Institution: Fox Chase Cancer Center
Hypothesis
The study aims to identify and characterize a new member of the MRP/cMOAT transporter family.
Conclusion
The study successfully isolated and characterized a new transporter, MOAT-E, which may play a role in detoxification processes in the kidney and liver.
Supporting Evidence
- MOAT-E is a new transporter related to the MRP/cMOAT family.
- It is expressed specifically in the kidney and liver.
- The transporter may be involved in detoxifying harmful substances.
Takeaway
Scientists found a new transporter in the body that helps remove harmful substances, especially in the kidneys and liver.
Methodology
The study involved the isolation and analysis of a human cDNA encoding a new transporter.
Digital Object Identifier (DOI)
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