ECMO as a Bridge to Heart Transplantation
Author Information
Author(s): Laali Mojgan MD, PhD, Ponnaiah Maharajah PhD, Coutance Guillaume MD, PhD, Hekimian Guillaume MD, D'Alessandro Cosimo MD, Demondion Pierre MD, Lebreton Guillaume MD, PhD, Leprince Pascal MD, PhD
Primary Institution: Sorbonne Université, APHP, Groupe Hospitalier Pitié-Salpétrière, Institute of Cardiology, Paris, France
Hypothesis
What are the outcomes of patients directly bridged with venoarterial extracorporeal membrane oxygenation to heart transplantation?
Conclusion
ECMO as a direct bridge to heart transplantation shows similar outcomes to standard cohorts of patients.
Supporting Evidence
- Patients on ECMO had similar 1-year and 9-year survival rates compared to those without ECMO.
- ECMO group had a shorter waiting list time due to emergency allocation.
- Recipients in the ECMO group had better renal function at the time of transplantation.
- Post-transplant ECMO support was more frequently maintained in the ECMO group.
Takeaway
Doctors used a machine to help patients' hearts while they waited for a transplant, and it worked just as well as other methods.
Methodology
A single-center retrospective study comparing 317 patients on ECMO to 835 patients without ECMO.
Potential Biases
Patients who died during the waiting period were not included in the analysis.
Limitations
The study is retrospective and lacks data on the severity of shock before ECMO.
Participant Demographics
The study included 1152 adult patients, with 317 on ECMO and 835 in a standard cohort.
Statistical Information
P-Value
.021
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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